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Discovery of a novel activator of 5-lipoxygenase from an anacardic acid derived compound collection

Lipoxygenases (LOXs) and cyclooxygenases (COXs) metabolize poly-unsaturated fatty acids into inflammatory signaling molecules. Modulation of the activity of these enzymes may provide new approaches for therapy of inflammatory diseases. In this study, we screened novel anacardic acid derivatives as m...

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Detalhes bibliográficos
Main Authors: Wisastra, Rosalina, Kok, Petra A.M, Eleftheriadis, Nikolaos, Baumgartner, Matthew P., Camacho, Carlos J., Haisma, Hidde J., Dekker, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017091/
https://ncbi.nlm.nih.gov/pubmed/24231650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.10.015
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