Quantification Assays for Total and Polyglutamine-Expanded Huntingtin Proteins

The expansion of a CAG trinucleotide repeat in the huntingtin gene, which produces huntingtin protein with an expanded polyglutamine tract, is the cause of Huntington's disease (HD). Recent studies have reported that RNAi suppression of polyglutamine-expanded huntingtin (mutant HTT) in HD anima...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Macdonald, Douglas, Tessari, Michela A., Boogaard, Ivette, Smith, Melanie, Pulli, Kristiina, Szynol, Agnieszka, Albertus, Faywell, Lamers, Marieke B. A. C., Dijkstra, Sipke, Kordt, Daniel, Reindl, Wolfgang, Herrmann, Frank, McAllister, George, Fischer, David F., Munoz-Sanjuan, Ignacio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2014
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016121/
https://ncbi.nlm.nih.gov/pubmed/24816435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096854
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