Chargement en cours...
Impaired Heat Shock Response in Cells Expressing Full-Length Polyglutamine-Expanded Huntingtin
The molecular mechanisms by which polyglutamine (polyQ)-expanded huntingtin (Htt) causes neurodegeneration in Huntington's disease (HD) remain unclear. The malfunction of cellular proteostasis has been suggested as central in HD pathogenesis and also as a target of therapeutic interventions for...
Enregistré dans:
| Auteurs principaux: | , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2012
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3359295/ https://ncbi.nlm.nih.gov/pubmed/22649566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037929 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|