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FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H(2)O(2) accumulation
Besides their cell-damaging effects in the setting of oxidative stress, reactive oxygen species (ROS) play an important role in physiological intracellular signalling by triggering proliferation and survival. FoxO transcription factors counteract ROS generation by upregulating antioxidant enzymes. H...
Gorde:
| Egile Nagusiak: | , , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Pub. Group
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4015330/ https://ncbi.nlm.nih.gov/pubmed/24781012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4773 |
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