A pRb-responsive, RGD-modified, and Hyaluronidase-armed Canine Oncolytic Adenovirus for Application in Veterinary Oncology

Human and canine cancer share similarities such as genetic and molecular aspects, biological complexity, tumor epidemiology, and targeted therapeutic treatment. Lack of good animal models for human adenovirotherapy has spurred the use of canine adenovirus 2-based oncolytic viruses. We have construct...

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Detalhes bibliográficos
Main Authors: Laborda, Eduardo, Puig-Saus, Cristina, Rodriguez-García, Alba, Moreno, Rafael, Cascalló, Manel, Pastor, Josep, Alemany, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015225/
https://ncbi.nlm.nih.gov/pubmed/24448161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.7
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