Evidence of Anti-tumoral Efficacy in an Immune Competent Setting with an iRGD-Modified Hyaluronidase-Armed Oncolytic Adenovirus

To enhance adenovirus-mediated oncolysis, different approaches that tackle the selectivity, tumor penetration, and spreading potential of oncolytic adenoviruses have been reported. We have previously demonstrated that insertion of the internalizing Arginine-Glycine-Aspartic (iRGD) tumor-penetrating...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Ther Oncolytics
Autori principali: Al-Zaher, Ahmed Abdullah, Moreno, Rafael, Fajardo, Carlos Alberto, Arias-Badia, Marcel, Farrera, Martí, de Sostoa, Jana, Rojas, Luis Alfonso, Alemany, Ramon
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Gene & Cell Therapy 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991897/
https://ncbi.nlm.nih.gov/pubmed/29888319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2018.01.003
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi