Evidence of Anti-tumoral Efficacy in an Immune Competent Setting with an iRGD-Modified Hyaluronidase-Armed Oncolytic Adenovirus

To enhance adenovirus-mediated oncolysis, different approaches that tackle the selectivity, tumor penetration, and spreading potential of oncolytic adenoviruses have been reported. We have previously demonstrated that insertion of the internalizing Arginine-Glycine-Aspartic (iRGD) tumor-penetrating...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Ther Oncolytics
Egile Nagusiak: Al-Zaher, Ahmed Abdullah, Moreno, Rafael, Fajardo, Carlos Alberto, Arias-Badia, Marcel, Farrera, Martí, de Sostoa, Jana, Rojas, Luis Alfonso, Alemany, Ramon
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Gene & Cell Therapy 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5991897/
https://ncbi.nlm.nih.gov/pubmed/29888319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2018.01.003
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