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Using Pulmozyme DNase Treatment in Lentiviral Vector Production

In the production of lentiviral vector for clinical studies the purity of the final product is of vital importance. To remove plasmid and producer cell line DNA, investigators have incubated the vector product with Benzonase, a bacterially derived DNase. As an alternative we investigated the use of...

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Dettagli Bibliografici
Autori principali: Shaw, Aaron, Bischof, Daniela, Jasti, Aparna, Ernstberger, Aaron, Hawkins, Troy, Cornetta, Kenneth
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015072/
https://ncbi.nlm.nih.gov/pubmed/22428981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2011.204
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