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Using Pulmozyme DNase Treatment in Lentiviral Vector Production

In the production of lentiviral vector for clinical studies the purity of the final product is of vital importance. To remove plasmid and producer cell line DNA, investigators have incubated the vector product with Benzonase, a bacterially derived DNase. As an alternative we investigated the use of...

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Autores principales: Shaw, Aaron, Bischof, Daniela, Jasti, Aparna, Ernstberger, Aaron, Hawkins, Troy, Cornetta, Kenneth
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015072/
https://ncbi.nlm.nih.gov/pubmed/22428981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2011.204
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