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Replication-competent Lentivirus Analysis of Clinical Grade Vector Products

Lentiviral vectors are now in clinical trials for a variety of inherited and acquired disorders. A challenge for moving any viral vector into the clinic is the ability to screen the vector product for the presence of replication-competent virus. Assay development for replication-competent lentivirus...

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Hlavní autoři: Cornetta, Kenneth, Yao, Jing, Jasti, Aparna, Koop, Sue, Douglas, Makhaila, Hsu, David, Couture, Larry A, Hawkins, Troy, Duffy, Lisa
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048188/
https://ncbi.nlm.nih.gov/pubmed/21179010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.278
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