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Using Pulmozyme DNase Treatment in Lentiviral Vector Production

In the production of lentiviral vector for clinical studies the purity of the final product is of vital importance. To remove plasmid and producer cell line DNA, investigators have incubated the vector product with Benzonase, a bacterially derived DNase. As an alternative we investigated the use of...

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Detalhes bibliográficos
Main Authors: Shaw, Aaron, Bischof, Daniela, Jasti, Aparna, Ernstberger, Aaron, Hawkins, Troy, Cornetta, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015072/
https://ncbi.nlm.nih.gov/pubmed/22428981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2011.204
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