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Using Pulmozyme DNase Treatment in Lentiviral Vector Production

In the production of lentiviral vector for clinical studies the purity of the final product is of vital importance. To remove plasmid and producer cell line DNA, investigators have incubated the vector product with Benzonase, a bacterially derived DNase. As an alternative we investigated the use of...

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Main Authors: Shaw, Aaron, Bischof, Daniela, Jasti, Aparna, Ernstberger, Aaron, Hawkins, Troy, Cornetta, Kenneth
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015072/
https://ncbi.nlm.nih.gov/pubmed/22428981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2011.204
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