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Analysis of Particle Content of Recombinant Adeno-Associated Virus Serotype 8 Vectors by Ion-Exchange Chromatography

Advances in adeno-associated virus (AAV)-mediated gene therapy have brought the possibility of commercial manufacturing of AAV vectors one step closer. To realize this prospect, a parallel effort with the goal of ever-increasing sophistication for AAV vector production technology and supporting assa...

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Autori principali: Lock, Martin, Alvira, Mauricio R., Wilson, James M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015067/
https://ncbi.nlm.nih.gov/pubmed/22428980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2011.217
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