Pharmacokinetic interaction of rifapentine and raltegravir in healthy volunteers

OBJECTIVES: Latent tuberculosis infection and tuberculosis disease are prevalent worldwide. However, antimycobacterial rifamycins have drug interactions with many antiretroviral drugs. We evaluated the effect of rifapentine on the pharmacokinetic properties of raltegravir. METHODS: In this open-labe...

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Main Authors: Weiner, Marc, Egelund, Eric F., Engle, Melissa, Kiser, Melissa, Prihoda, Thomas J., Gelfond, Jonathan A. L., Mac Kenzie, William, Peloquin, Charles A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014856/
https://ncbi.nlm.nih.gov/pubmed/24343893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt483
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