Pharmacokinetic interaction of rifapentine and raltegravir in healthy volunteers

OBJECTIVES: Latent tuberculosis infection and tuberculosis disease are prevalent worldwide. However, antimycobacterial rifamycins have drug interactions with many antiretroviral drugs. We evaluated the effect of rifapentine on the pharmacokinetic properties of raltegravir. METHODS: In this open-labe...

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Detalhes bibliográficos
Main Authors: Weiner, Marc, Egelund, Eric F., Engle, Melissa, Kiser, Melissa, Prihoda, Thomas J., Gelfond, Jonathan A. L., Mac Kenzie, William, Peloquin, Charles A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014856/
https://ncbi.nlm.nih.gov/pubmed/24343893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt483
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