Pharmacokinetic interaction of rifapentine and raltegravir in healthy volunteers

OBJECTIVES: Latent tuberculosis infection and tuberculosis disease are prevalent worldwide. However, antimycobacterial rifamycins have drug interactions with many antiretroviral drugs. We evaluated the effect of rifapentine on the pharmacokinetic properties of raltegravir. METHODS: In this open-labe...

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Bibliographische Detailangaben
Hauptverfasser: Weiner, Marc, Egelund, Eric F., Engle, Melissa, Kiser, Melissa, Prihoda, Thomas J., Gelfond, Jonathan A. L., Mac Kenzie, William, Peloquin, Charles A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014856/
https://ncbi.nlm.nih.gov/pubmed/24343893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt483
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