Pharmacokinetic interaction of rifapentine and raltegravir in healthy volunteers

OBJECTIVES: Latent tuberculosis infection and tuberculosis disease are prevalent worldwide. However, antimycobacterial rifamycins have drug interactions with many antiretroviral drugs. We evaluated the effect of rifapentine on the pharmacokinetic properties of raltegravir. METHODS: In this open-labe...

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Autors principals: Weiner, Marc, Egelund, Eric F., Engle, Melissa, Kiser, Melissa, Prihoda, Thomas J., Gelfond, Jonathan A. L., Mac Kenzie, William, Peloquin, Charles A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014856/
https://ncbi.nlm.nih.gov/pubmed/24343893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkt483
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