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Cycles of Transient High-Dose Cyclophosphamide Administration and Oncolytic Adenovirus Vector Intratumoral Injection for Long Term Tumor Suppression in Syrian Hamsters

Immune responses against oncolytic adenovirus (Ad) vectors are thought to limit vector anti-tumor efficacy. In Syrian hamsters, which are immunocompetent and whose tumors and normal tissues are permissive for replication of Ad5-based oncolytic Ad vectors, treating with high-dose cyclophosphamide to...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Dhar, Debanjan, Toth, Karoly, Wold, William S.M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013531/
https://ncbi.nlm.nih.gov/pubmed/24722357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2014.13
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