Oncogene-induced reactive oxygen species fuel hyperproliferation and DNA damage response activation

Oncogene-induced reactive oxygen species (ROS) have been proposed to be signaling molecules that mediate proliferative cues. However, ROS may also cause DNA damage and proliferative arrest. How these apparently opposite roles can be reconciled, especially in the context of oncogene-induced cellular...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ogrunc, M, Di Micco, R, Liontos, M, Bombardelli, L, Mione, M, Fumagalli, M, Gorgoulis, V G, d'Adda di Fagagna, F
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2014
विषय:
Original Paper
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013514/
https://ncbi.nlm.nih.gov/pubmed/24583638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.16
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