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FMRP S499 Is Phosphorylated Independent of mTORC1-S6K1 Activity
Hyperactive mammalian target of rapamycin (mTOR) is associated with cognitive deficits in several neurological disorders including tuberous sclerosis complex (TSC). The phosphorylation of the mRNA-binding protein FMRP reportedly depends on mTOR complex 1 (mTORC1) activity via p70 S6 kinase 1 (S6K1)....
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4013076/ https://ncbi.nlm.nih.gov/pubmed/24806451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096956 |
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