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Sorafenib and HDAC inhibitors synergize with TRAIL to kill tumor cells

The present studies were designed to compare and contrast the abilities of TRAIL (death receptor agonist) and obatoclax (BCL-2 family inhibitor) to enhance [sorafenib + HDAC inhibitor] toxicity in GI tumor cells. Sorafenib and HDAC inhibitor treatment required expression of CD95 to kill GI tumor cel...

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Autori principali: Hamed, Hossein A., Yamaguchi, Yukihiro, Fisher, Paul B., Grant, Steven, Dent, Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4012564/
https://ncbi.nlm.nih.gov/pubmed/23674352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24362
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