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Sorafenib and HDAC inhibitors synergize with TRAIL to kill tumor cells
The present studies were designed to compare and contrast the abilities of TRAIL (death receptor agonist) and obatoclax (BCL-2 family inhibitor) to enhance [sorafenib + HDAC inhibitor] toxicity in GI tumor cells. Sorafenib and HDAC inhibitor treatment required expression of CD95 to kill GI tumor cel...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4012564/ https://ncbi.nlm.nih.gov/pubmed/23674352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24362 |
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