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Studies on the antiproliferative effects of tropolone derivatives in Jurkat T-lymphocyte cells

Thujaplicins are tropolone-derived natural products with antiproliferative properties. We recently reported that certain tropolones potently and selectively target histone deacetylases (HDAC) and inhibit the growth of hematological cell lines. Here, we investigated the mechanisms by which these comp...

詳細記述

保存先:
書誌詳細
主要な著者: Ononye, Sophia N., Van Heyst, Michael D., Giardina, Charles, Wright, Dennis L., Anderson, Amy C.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011186/
https://ncbi.nlm.nih.gov/pubmed/24613456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.02.018
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