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Toward isozyme-selective inhibitors of histone deacetylase as therapeutic agents for the treatment of cancer
Since post-translational modifications of proteins are key mechanisms for controlling cellular function, targeting the machinery involved in these modifications offers new opportunities for the development of therapeutic agents. The histone deacetylases (HDACs) represent an important family of enzym...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3807748/ https://ncbi.nlm.nih.gov/pubmed/24163736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/ppa.12.21 |
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