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Highly efficient targeted mutagenesis in axolotl using Cas9 RNA-guided nuclease

Among tetrapods, only urodele salamanders, such as the axolotl Ambystoma mexicanum, can completely regenerate limbs as adults. The mystery of why salamanders, but not other animals, possess this ability has for generations captivated scientists seeking to induce this phenomenon in other vertebrates....

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Flowers, G. Parker, Timberlake, Andrew T., Mclean, Kaitlin C., Monaghan, James R., Crews, Craig M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011087/
https://ncbi.nlm.nih.gov/pubmed/24764077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.105072
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