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Highly efficient targeted mutagenesis in axolotl using Cas9 RNA-guided nuclease
Among tetrapods, only urodele salamanders, such as the axolotl Ambystoma mexicanum, can completely regenerate limbs as adults. The mystery of why salamanders, but not other animals, possess this ability has for generations captivated scientists seeking to induce this phenomenon in other vertebrates....
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4011087/ https://ncbi.nlm.nih.gov/pubmed/24764077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.105072 |
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