Genome editing with RNA-guided Cas9 nuclease in Zebrafish embryos

Recent advances with the type II clustered regularly interspaced short palindromic repeats (CRISPR) system promise an improved approach to genome editing. However, the applicability and efficiency of this system in model organisms, such as zebrafish, are little studied. Here, we report that RNA-guid...

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Autors principals: Chang, Nannan, Sun, Changhong, Gao, Lu, Zhu, Dan, Xu, Xiufei, Zhu, Xiaojun, Xiong, Jing-Wei, Xi, Jianzhong Jeff
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3616424/
https://ncbi.nlm.nih.gov/pubmed/23528705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.45
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