CRISPR/Cas9-deaminase enables robust base editing in Rhodobacter sphaeroides 2.4.1

BACKGROUND: CRISPR/Cas9 systems have been repurposed as canonical genome editing tools in a variety of species, but no application for the model strain Rhodobacter sphaeroides 2.4.1 was unveiled. RESULTS: Here we showed two kinds of programmable base editing systems, cytosine base editors (CBEs) and...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Microb Cell Fact
Huvudupphovsmän: Luo, Yufeng, Ge, Mei, Wang, Bolun, Sun, Changhong, Wang, Junyi, Dong, Yuyang, Xi, Jianzhong Jeff
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2020
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183636/
https://ncbi.nlm.nih.gov/pubmed/32334589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01345-w
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk