CRISPR/Cas9-deaminase enables robust base editing in Rhodobacter sphaeroides 2.4.1

BACKGROUND: CRISPR/Cas9 systems have been repurposed as canonical genome editing tools in a variety of species, but no application for the model strain Rhodobacter sphaeroides 2.4.1 was unveiled. RESULTS: Here we showed two kinds of programmable base editing systems, cytosine base editors (CBEs) and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Microb Cell Fact
Egile Nagusiak: Luo, Yufeng, Ge, Mei, Wang, Bolun, Sun, Changhong, Wang, Junyi, Dong, Yuyang, Xi, Jianzhong Jeff
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2020
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183636/
https://ncbi.nlm.nih.gov/pubmed/32334589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01345-w
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak