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CRISPR/Cas9-deaminase enables robust base editing in Rhodobacter sphaeroides 2.4.1
BACKGROUND: CRISPR/Cas9 systems have been repurposed as canonical genome editing tools in a variety of species, but no application for the model strain Rhodobacter sphaeroides 2.4.1 was unveiled. RESULTS: Here we showed two kinds of programmable base editing systems, cytosine base editors (CBEs) and...
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| Publié dans: | Microb Cell Fact |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7183636/ https://ncbi.nlm.nih.gov/pubmed/32334589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-020-01345-w |
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