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Regulation of proximal tubule vacuolar H(+)-ATPase by PKA and AMP-activated protein kinase

The vacuolar H(+)-ATPase (V-ATPase) mediates ATP-driven H(+) transport across membranes. This pump is present at the apical membrane of kidney proximal tubule cells and intercalated cells. Defects in the V-ATPase and in proximal tubule function can cause renal tubular acidosis. We examined the role...

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Autori principali: Al-bataineh, Mohammad M., Gong, Fan, Marciszyn, Allison L., Myerburg, Michael M., Pastor-Soler, Núria M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010682/
https://ncbi.nlm.nih.gov/pubmed/24553431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00362.2013
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