PKA Regulates Vacuolar H(+)-ATPase Localization and Activity via Direct Phosphorylation of the A Subunit in Kidney Cells

The vacuolar H(+)-ATPase (V-ATPase) is a major contributor to luminal acidification in epithelia of Wolffian duct origin. In both kidney-intercalated cells and epididymal clear cells, cAMP induces V-ATPase apical membrane accumulation, which is linked to proton secretion. We have shown previously th...

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Detalhes bibliográficos
Main Authors: Alzamora, Rodrigo, Thali, Ramon F., Gong, Fan, Smolak, Christy, Li, Hui, Baty, Catherine J., Bertrand, Carol A., Auchli, Yolanda, Brunisholz, René A., Neumann, Dietbert, Hallows, Kenneth R., Pastor-Soler, Núria M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Membrane Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2915704/
https://ncbi.nlm.nih.gov/pubmed/20525692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.106278
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