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Vacuolar H(+)-ATPase apical accumulation in kidney intercalated cells is regulated by PKA and AMP-activated protein kinase

The vacuolar H(+)-ATPase (V-ATPase) in type A kidney intercalated cells is a major contributor to acid excretion in the collecting duct. The mechanisms of V-ATPase-trafficking regulation in kidney intercalated cells have not been well-characterized. In developmentally related epididymal clear cells,...

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Bibliographic Details
Main Authors: Gong, Fan, Alzamora, Rodrigo, Smolak, Christy, Li, Hui, Naveed, Sajid, Neumann, Dietbert, Hallows, Kenneth R., Pastor-Soler, Núria M.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867405/
https://ncbi.nlm.nih.gov/pubmed/20147366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00645.2009
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