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Regulation of proximal tubule vacuolar H(+)-ATPase by PKA and AMP-activated protein kinase
The vacuolar H(+)-ATPase (V-ATPase) mediates ATP-driven H(+) transport across membranes. This pump is present at the apical membrane of kidney proximal tubule cells and intercalated cells. Defects in the V-ATPase and in proximal tubule function can cause renal tubular acidosis. We examined the role...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010682/ https://ncbi.nlm.nih.gov/pubmed/24553431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00362.2013 |
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