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The regulation of N-terminal Huntingtin (Htt552) accumulation by Beclin1
AIM: Huntingtin protein (Htt) was a neuropathological hallmark in human Huntington's Disease. The study aimed to investigate whether the macroautophagy regulator, Beclin1, was involved in the degradation of Htt. METHODS: PC12 cells and primary cultured brain neurons of rats were examined. pDC31...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010368/ https://ncbi.nlm.nih.gov/pubmed/22543707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.14 |
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