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Effects of liraglutide and sibutramine on food intake, palatability, body weight and glucose tolerance in the gubra DIO-rats

AIM: To validate the gubra DIO-rats as a useful animal model of human obesity. METHODS: The gubra diet-induced obesity (DIO) rat model was based on male Sprague-Dawley rats with ad libitum access to regular chow and a palatable diet rich in fat and sugar. To evaluate the versatility of the gubra DIO...

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Hlavní autoři: Hansen, Gitte, Jelsing, Jacob, Vrang, Niels
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010326/
https://ncbi.nlm.nih.gov/pubmed/22301859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.168
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