A Hamster Model of Diet-Induced Obesity for Preclinical Evaluation of Anti-Obesity, Anti-Diabetic and Lipid Modulating Agents

AIM: Unlike rats and mice, hamsters develop hypercholesterolemia, and hypertriglyceridemia when fed a cholesterol-rich diet. Because hyperlipidemia is a hallmark of human obesity, we aimed to develop and characterize a novel diet-induced obesity (DIO) and hypercholesterolemia Golden Syrian hamster m...

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發表在:PLoS One
Main Authors: Dalbøge, Louise S., Pedersen, Philip J., Hansen, Gitte, Fabricius, Katrine, Hansen, Henrik B., Jelsing, Jacob, Vrang, Niels
格式: Artigo
語言:Inglês
出版: Public Library of Science 2015
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4534139/
https://ncbi.nlm.nih.gov/pubmed/26266945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135634
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