Characterization of combined linagliptin and Y2R agonist treatment in diet-induced obese mice

Dipeptidyl peptidase IV (DPP-IV) inhibitors improve glycemic control by prolonging the action of glucagon-like peptide-1 (GLP-1). In contrast to GLP-1 analogues, DPP-IV inhibitors are weight-neutral. DPP-IV cleavage of PYY and NPY gives rise to PYY(3-36) and NPY(3-36) which exert potent anorectic ac...

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Udgivet i:Sci Rep
Main Authors: Hansen, Henrik H., Grønlund, Rikke V., Baader-Pagler, Tamara, Haebel, Peter, Tammen, Harald, Larsen, Leif Kongskov, Jelsing, Jacob, Vrang, Niels, Klein, Thomas
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8044192/
https://ncbi.nlm.nih.gov/pubmed/33850212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-87539-7
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