The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss

Liraglutide is a glucagon-like peptide-1 (GLP-1) analog marketed for the treatment of type 2 diabetes. Besides lowering blood glucose, liraglutide also reduces body weight. It is not fully understood how liraglutide induces weight loss or to what degree liraglutide acts directly in the brain. Here,...

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Main Authors: Secher, Anna, Jelsing, Jacob, Baquero, Arian F., Hecksher-Sørensen, Jacob, Cowley, Michael A., Dalbøge, Louise S., Hansen, Gitte, Grove, Kevin L., Pyke, Charles, Raun, Kirsten, Schäffer, Lauge, Tang-Christensen, Mads, Verma, Saurabh, Witgen, Brent M., Vrang, Niels, Bjerre Knudsen, Lotte
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4215190/
https://ncbi.nlm.nih.gov/pubmed/25202980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI75276
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