The IL-1β Receptor Antagonist SER140 Postpones the Onset of Diabetes in Female Nonobese Diabetic Mice

The cytokine interleukin-1β (IL-1β) is known to stimulate proinflammatory immune responses and impair β-cell function and viability, all critical events in the pathogenesis of type 1 diabetes (T1D). Here we evaluate the effect of SER140, a small peptide IL-1β receptor antagonist, on diabetes progres...

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Detalles Bibliográficos
Publicado en:J Diabetes Res
Main Authors: Cucak, Helena, Hansen, Gitte, Vrang, Niels, Skarsfeldt, Torben, Steiness, Eva, Jelsing, Jacob
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4756207/
https://ncbi.nlm.nih.gov/pubmed/26953152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/7484601
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