Thrombin induced connective tissue growth factor expression in rat vascular smooth muscle cells via the PAR-1/JNK/AP-1 pathway

AIM: To investigate the signaling pathways involved in thrombin-induced connective tissue growth factor (CTGF) expression in rat vascular smooth muscle cells (VSMCs). METHODS: Experiments were preformed on primary rat aortic smooth muscle cells (RASMCs) and a rat VSMC line (A10). CTGF protein levels...

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Main Authors: Ko, Wen-chin, Chen, Bing-chang, Hsu, Ming-jen, Tsai, Chia-ti, Hong, Chuang-ye, Lin, Chien-huang
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010264/
https://ncbi.nlm.nih.gov/pubmed/22212430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.178
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