Estrogen modulates vascular smooth muscle cell function through downregulation of SIRT1

BACKGROUND: There are sex differences in the incidence and severity of cardiovascular disease. Although an estrogen-mediated vasculoprotective effect is widely accepted, clinical trial results have been conflicting and the detailed mechanisms are still unclear. Sirtuin 1 (SIRT1), a class III histone...

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Vydáno v:Oncotarget
Hlavní autoři: Lee, Chien-Hsing, Su, Sheng-Chiang, Chiang, Chi-Fu, Chien, Chu-Yen, Hsu, Chia-Chen, Yu, Tzu-Yi, Huang, Shih-Ming, Shieh, Yi-Shing, Kao, Hong-Wei, Tsai, Chien-Sung, Hung, Yi-Jen, Lin, Chih-Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5746363/
https://ncbi.nlm.nih.gov/pubmed/29299128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22546
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