Mycobacterium tuberculosis induces connective tissue growth factor expression through the TLR2-JNK–AP-1 pathway in human lung fibroblasts

Mycobacterium tuberculosis (M.tb) infection in lung causes pulmonary fibrosis, which leads to the irreversible reduction of pulmonary function. Fibrotic protein connective tissue growth factor (CTGF) expression has been confirmed to play a crucial role in lung fibrosis. However, the underlying signa...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Lee, Hong-Sheng, Hua, Hung-Sheng, Wang, Cheng-Hui, Yu, Ming-Chih, Chen, Bing-Chang, Lin, Chien-Huang
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902670/
https://ncbi.nlm.nih.gov/pubmed/31451010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201900487R
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