Specificity of Anti-Tau Antibodies when Analyzing Mice Models of Alzheimer's Disease: Problems and Solutions

Aggregates of hyperphosphorylated tau protein are found in a group of diseases called tauopathies, which includes Alzheimer's disease. The causes and consequences of tau hyperphosphorylation are routinely investigated in laboratory animals. Mice are the models of choice as they are easily amena...

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Main Authors: Petry, Franck R., Pelletier, Jérôme, Bretteville, Alexis, Morin, Françoise, Calon, Frédéric, Hébert, Sébastien S., Whittington, Robert A., Planel, Emmanuel
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008431/
https://ncbi.nlm.nih.gov/pubmed/24788298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094251
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