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Specificity of Anti-Tau Antibodies when Analyzing Mice Models of Alzheimer's Disease: Problems and Solutions

Aggregates of hyperphosphorylated tau protein are found in a group of diseases called tauopathies, which includes Alzheimer's disease. The causes and consequences of tau hyperphosphorylation are routinely investigated in laboratory animals. Mice are the models of choice as they are easily amena...

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Détails bibliographiques
Auteurs principaux: Petry, Franck R., Pelletier, Jérôme, Bretteville, Alexis, Morin, Françoise, Calon, Frédéric, Hébert, Sébastien S., Whittington, Robert A., Planel, Emmanuel
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008431/
https://ncbi.nlm.nih.gov/pubmed/24788298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094251
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