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Repeated cold exposures protect a mouse model of Alzheimer's disease against cold-induced tau phosphorylation
OBJECTIVE: Old age is associated with a rise in the incidence of Alzheimer's disease (AD) but also with thermoregulatory deficits. Indicative of a link between the two, hypothermia induces tau hyperphosphorylation. The 3xTg-AD mouse model not only develops tau and amyloid pathologies in the bra...
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| Publicado no: | Mol Metab |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6437631/ https://ncbi.nlm.nih.gov/pubmed/30770297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.01.008 |
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