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Specificity of Anti-Tau Antibodies when Analyzing Mice Models of Alzheimer's Disease: Problems and Solutions

Aggregates of hyperphosphorylated tau protein are found in a group of diseases called tauopathies, which includes Alzheimer's disease. The causes and consequences of tau hyperphosphorylation are routinely investigated in laboratory animals. Mice are the models of choice as they are easily amena...

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Detalhes bibliográficos
Main Authors: Petry, Franck R., Pelletier, Jérôme, Bretteville, Alexis, Morin, Françoise, Calon, Frédéric, Hébert, Sébastien S., Whittington, Robert A., Planel, Emmanuel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008431/
https://ncbi.nlm.nih.gov/pubmed/24788298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094251
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