AMPK enhances the expression of pancreatic duodenal homeobox-1 via PPARα, but not PPARγ, in rat insulinoma cell line INS-1

AIM: To investigate whether AMP-activated protein kinase (AMPK) regulates the expression of pancreatic duodenal homeobox-1 (PDX-1), a β-cell-specific transcription factor and whether PPARα/γ is involved in the regulation of pancreatic β-cell lines after acute stimulation. METHODS: Rat insulinoma cel...

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Autors principals: Guo, Hua, Sun, Shui, Zhang, Xu, Zhang, Xiu-juan, Gao, Ling, Zhao, Jia-jun
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4007814/
https://ncbi.nlm.nih.gov/pubmed/20644547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.78
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