Notch1 Activation Up-Regulates Pancreatic and Duodenal Homeobox-1

Transcription factor pancreatic and duodenal homeobox-1 (PDX-1) plays an essential role in pancreatic development, β-cell differentiation, maintenance of normal β-cell function and tumorigenesis. PDX-1 expression is tightly controlled through a variety of mechanisms under different cellular contexts...

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Bibliografiske detaljer
Main Authors: Liu, Shi-He, Zhou, Guisheng, Yu, Juehua, Wu, James, Nemunaitis, John, Senzer, Neil, Dawson, David, Li, Min, Fisher, William E., Brunicardi, F. Charles
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924823/
https://ncbi.nlm.nih.gov/pubmed/24705209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes4030358
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