Down-regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5: a novel mechanism for inhibition of cellular proliferation and insulin secretion by somatostatin

Somatostatin (SST) is a regulatory peptide and acts as an endogenous inhibitory regulator of the secretory and proliferative responses of target cells. SST’s actions are mediated by a family of seven transmembrane domain G protein-coupled receptors that comprise five distinct subtypes (SSTR1-5). SST...

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Hlavní autoři: Zhou, Guisheng, Sinnett-Smith, Jim, Liu, Shi-He, Yu, Juehua, Wu, James, Sanchez, Robbi, Pandol, Stephen J., Abrol, Ravinder, Nemunaitis, John, Rozengurt, Enrique, Brunicardi, F. Charles
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4069483/
https://ncbi.nlm.nih.gov/pubmed/25009500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00226
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