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AMPK enhances the expression of pancreatic duodenal homeobox-1 via PPARα, but not PPARγ, in rat insulinoma cell line INS-1
AIM: To investigate whether AMP-activated protein kinase (AMPK) regulates the expression of pancreatic duodenal homeobox-1 (PDX-1), a β-cell-specific transcription factor and whether PPARα/γ is involved in the regulation of pancreatic β-cell lines after acute stimulation. METHODS: Rat insulinoma cel...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007814/ https://ncbi.nlm.nih.gov/pubmed/20644547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.78 |
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