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Activated AMPK inhibits PPAR-α and PPAR-γ transcriptional activity in hepatoma cells

AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptor-α (PPAR-α) are critical regulators of short-term and long-term fatty acid oxidation, respectively. We examined whether the activities of these molecules were coordinately regulated. H4IIEC3 cells were transfected with...

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Detalhes bibliográficos
Main Authors: Sozio, Margaret S., Lu, Changyue, Zeng, Yan, Liangpunsakul, Suthat, Crabb, David W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191559/
https://ncbi.nlm.nih.gov/pubmed/21700905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00432.2010
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