Inhibitory effect of ethanol on AMPK phosphorylation is mediated in part through elevated ceramide levels

Ethanol treatment of cultured hepatoma cells and of mice inhibited the activity of AMP-activated protein kinase (AMPK). This study shows that the inhibitory effect of ethanol on AMPK phosphorylation is exerted through the inhibition of the phosphorylation of upstream kinases and the activation of pr...

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Hlavní autoři: Liangpunsakul, Suthat, Sozio, Margaret S., Shin, Eric, Zhao, Zhenwen, Xu, Yan, Ross, Ruth A., Zeng, Yan, Crabb, David W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2010
Témata:
Liver and Biliary Tract
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774334/
https://ncbi.nlm.nih.gov/pubmed/20224005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00482.2009
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