Decreased Expression and Induced Nucleocytoplasmic Translocation of Pancreatic and Duodenal Homeobox 1 in INS-1 Cells Exposed to High Glucose and Palmitate

BACKGROUND: Type 2 diabetes mellitus (T2DM) is often accompanied by increased levels of circulating fatty acid. Elevations in fatty acids and glucose for prolonged periods of time have been suggested to cause progressive dysfunction or apoptosis of pancreatic beta cells in T2DM. However, the precise...

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Main Authors: Ryu, Gyeong Ryul, Yoo, Jun Mo, Lee, Esder, Ko, Seung-Hyun, Ahn, Yu-Bae, Song, Ki-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Diabetes Association 2011
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3080567/
https://ncbi.nlm.nih.gov/pubmed/21537415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/dmj.2011.35.1.65
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