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Hypoxia Increases β-Cell Death by Activating Pancreatic Stellate Cells within the Islet
BACKGROUND: Hypoxia can occur in pancreatic islets in type 2 diabetes mellitus. Pancreatic stellate cells (PSCs) are activated during hypoxia. Here we aimed to investigate whether PSCs within the islet are also activated in hypoxia, causing β-cell injury. METHODS: Islet and primary PSCs were isolate...
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| Publicat a: | Diabetes Metab J |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Korean Diabetes Association
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7801750/ https://ncbi.nlm.nih.gov/pubmed/32431113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4093/dmj.2019.0181 |
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